Gather all ingredients. Dotdash Meredith Food Studios
Bring a large pot of lightly salted water to a boil. Add penne and cook in boiling water, stirring occasionally, until tender yet firm to the bite, about 11 minutes. Drain and set aside. Dotdash Meredith Food Studios
Heat olive oil in a large skillet or wok over medium heat. Sauté prosciutto, garlic, and red pepper flakes in hot oil for 1 minute. Dotdash Meredith Food Studios
Mix in tomatoes and cook for 3 minutes. Dotdash Meredith Food Studios
Stir in cream and vodka; simmer until sauce is thickened, about 15 minutes. Dotdash Meredith Food Studios
Stir Parmesan and basil into sauce until well combined. Season with salt. Dotdash Meredith Food Studios
Add penne and toss until evenly coated. Dotdash Meredith Food Studios
Penne Russo à la Vodka · Dinner Match Lab | Dinner Match Lab